Case StudyOptical Genome Mapping
About This Project
Our client, a startup, was developing a new nanochip fluidic device for identification of genomic variation, with intended application to clinical care, research, and therapeutics. The client was looking for a development partner who could develop the complete software solution for the instrument, including GUI, workflow image processing, device control and reporting in parallel with their team, who were developing the instrument hardware.
- Challenges
- Approach & Solution
- Outcomes
• Existing approaches to optical sequencing lacked the digital resolution and efficiency to resolve structural variants at scale.
• Client personnel were primarily data scientists with no experience in product commercialization.
• Client wanted software development to begin prior to the target hardware platform being available, to optimize time-to-market.
• FS assembled a varied team with broad expertise to approach the UX/UI, device control, image processing, and embedded OS bring-up in parallel.
• FS image processing engineer worked in close collaboration with the client’s data scientists to develop the classification algorithm, iteratively improving the accuracy along the course of the engagement.
• All development was conducted incrementally with results delivered to the client for routine fast feedback.
• Project resulted in the initial release of a powerful and commercially successful optical genome mapping (OGM) tool for structural variant detection.
• Client was highly satisfied with product performance of 10x genome mapping in half an hour.